Associate Clinical Analyst II (US)

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com . Summary Shift: Tuesday-Saturday or Sunday-Thursday 9am-5pm ET How to Apply: Please submit your resume along with a cover letter (required for consideration) detailing your experience and motivation for applying. Applications without a cover letter will not be considered. The Associate Clinical Analyst II (ABMGG-eligible or active candidate) supports the interpretation of genetic findings and contributes to accurate diagnosis and case resolution through exome and genome sequencing. This entry-level role focuses on building foundational clinical analysis skills by assisting with case reviews under supervision, performing routine data interpretation tasks. Responsibilities include supporting variant classification activities, preparing accurate documentation, and contributing to internal database updates. The Associate Clinical Analyst II ensures timely documentation, maintains quality standards, and aids departmental initiatives through collaborative engagement and continuous learning. Job Responsibilities Perform clinical data analysis and case management to accurately interpret genetic findings. Establish phenotype-genotype correlations across diverse genetic disorders. Investigate and interpret clinical features of genetic conditions using internal resources and professional tools. Review and finalize genetic test reports, interpret variants, and curate internal databases. Serve as a subject matter expert for designated genes, disorders, tests, and workflows. Communicate with clients via email, phone, or other channels to support case resolution and provider engagement. May abstract clinical information from patient records. Performs literature reviews and database searches to support variant interpretation and classification. Meets or exceeds productivity and error standards as assigned by team lead. Documents evidence and rationale for variant classification in a clear, standardized format. Assist with development of variant-, gene-, or disease-specific test information and report language. Perform other duties as assigned to support the team or department. Credential-specific responsibilities include but are not limited to: ABMGG Certified: Fulfill responsibilities of Clinical Consultant as defined by CLIA (42 CFR 493.1457), including: Consultation Availability: Provides timely consultation to ordering providers regarding test selection, interpretation, and clinical correlation of laboratory results. Report Oversight: Reviews and ensures laboratory reports meet CLIA and CAP requirements for accuracy, completeness, and clinical relevance. Result Authorization: Approves and signs off on high-complexity test results in accordance with CLIA regulations. People Manager No Education, Experience, and Skills PhD in Biology, Genetics or related field, MD or DO with more than 2 years directly relevant experience in clinical diagnostics (including fellowship) Excellent verbal and written communication skills Demonstrated computer skills, including ability to maintain high proficiency with internal systems and Microsoft Office Suite and the Office 365 environment Prior experience with variant curation is preferred but not required Certificates, Licenses, Registrations ABMGG certification or equivalent, certified in at least one specialty OR board eligible Work Environment This is a fully remote position. The employee will work from a home office or other suitable remote location with reliable high-speed internet access. Work is performed in a climate-controlled environment using standard office equipment including computer, phone, and video conferencing tools. Your standard work schedule and hours will be established in collaboration with your leader and may be adjusted to align with evolving business needs. Physical Demands This is a sedentary role with physical demands including: Sitting for extended periods (up to 8 hours per day) Repetitive use of hands and fingers for typing and mouse operation Visual acuity for reading computer screens and documents Ability to communicate effectively in person, by phone, and via video Occasional standing, walking, and reaching for files or supplies Occasional lifting of up to 15 pounds (files, office supplies, equipment) Ability to commute to office location as required Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position. Acknowledgements The above job description is not intended to be an all-inclusive list of duties and standards of the position. Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor. #LI-REMOTE Pay Transparency, Budgeted Range $150,000 — $165,000 USD A culture that plays to win, because patients are counting on us​ At GeneDx, we're driven by urgency and purpose: helping patients get diagnosed earlier. Our mission, to empower everyone to live their healthiest life through genomics, drives our team to make a tangible impact each day – and shapes our culture where high standards, strong teamwork, and meaningful ownership are the norm. We act with intention, support one another, and deliver work we're proud to put our names on.​ Here’s what you can expect day to day:​ 1. Play like a champion (step up, redefine what’s possible, own it)​ We bring energy, focus, and a bias for action. We step up, take initiative, and deliver on our commitments – with quality, speed, and care.​ 2. Think bigger (stretch beyond, courage not consensus)​ We push past the obvious. We challenge assumptions, raise the bar, and make thoughtful, decisive calls — choosing progress over perfection.​ 3. Grow fast (be curious, speak up, be agile)​ We stay curious, ask questions, and share direct feedback with respect. We adapt quickly and keep learning through collaboration and continuous improvement.​ If you’re motivated by meaningful work, a fast-moving environment, and teammates who care deeply about outcomes, you’ll thrive at GeneDx. At GeneDx, we believe in taking care of our people. We provide competitive compensation and benefits that reflect local market practices and legal requirements in each country where we operate, helping employees thrive both professionally and personally. We welcome everyone regardless of their background. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, protected veteran status, disability, age, and other characteristics protected by law. GeneDx is a place where people from all backgrounds can make an impact. All privacy policy information can be found here .