Clinical Genomics Scientist III

Description JOB SUMMARY Baylor Genetics, one of the world leaders in clinical molecular genetics, is excited to announce an opening in the Clinical Genomics Interpretation (CGI) division. The Clinical Genomics Scientist analyzes clinical genetics data, curates variants and genes, and summarizes findings for clinical reports. Our scientists assist laboratory directors and R&D with validation of cutting-edge technologies and software platforms. The Clinical Genomics Scientist position is a remote work opportunity, with daily huddles, clear objectives, and flexible scheduling. Minimal on-site time at the headquarters in Houston, TX may be required. Come join our team from the comfort of your home office! KEY RESPONSIBILITES 50%: curation of variants, genes, and gene-disease correlations following ACMG guidelines, using our robust internal dataset, online resources, and published literature 30%: analyzing clinical genomics data, including next-generation sequencing, Sanger sequencing, metabolomics, and chromosomal microarray 10%: clinical report drafting 10%: validation, process refinement, presenting findings at meetings, and performing other duties as needed Performs other job-related duties as assigned. Adheres to Code of Conduct as outlined in the Baylor Genetics’ Compliance Program. QUALIFICATIONS Knowledge of genomic variation and its relationship to human disease Knowledge of literature curation methodologies Knowledge of variant detection, molecular mechanisms of disease, functional assays, and computational analysis Technical expertise in clinical medicine, genetics, genomics, or molecular biology Experience with data quality assessment Excellent verbal and written communication skills Proficiency in communicating an understanding of genetics details Knowledge of principles and practices of data analysis as applied to experimental results Experience in the application of ontologies for medical/biological annotation An understanding of bioinformatics analysis to identify variants within genomic data sets, and variant effect prediction algorithms (desired) Experience with use of Perl, Python, or other programming language (desired) Ability to create scripts and process large quantities of data (desired) QUALIFICATIONS: Clinical Genomic Scientist I Degree: PhD or MD level degree in clinical medicine, genetics, molecular biology, or an equivalent subject. Strong candidates with a Master’s degree and appropriate experience will be considered. Relevant experience: 0-2 years Certification (optional): MB(ASCP) Clinical Genomic Scientist II Degree: PhD or MD level degree in clinical medicine, genetics, molecular biology, or an equivalent subject. Strong candidates with a Master’s degree and appropriate experience will be considered. The Clinical Genomic Scientist II demonstrates a strong understanding of the principles of variant curation and genetic data analysis. Relevant experience: 2-4 years Certification (optional): MB(ASCP) Clinical Genomic Scientist III Degree: PhD or MD level degree in clinical medicine, genetics, molecular biology, or an equivalent subject. Strong candidates with a Master’s degree and appropriate experience will be considered. The Clinical Genomic Scientist III demonstrates a consistent high level of performance and leadership abilities. Relevant experience: 4-7 years Certification (optional): MB(ASCP) Senior Clinical Genomic Scientist Degree: PhD or MD level degree in clinical medicine, genetics, molecular biology, or an equivalent subject. The Senior Clinical Genomic Scientist demonstrates initiative, innovation, and process improvement abilities. Relevant experience: 7+ years Certification (optional): MB(ASCP) PHYSICAL DEMANDS AND WORK ENVIRONMENT Location: Onsite / Hybrid / Remote Frequently required to sit or stand Frequently required to utilize hand and finger dexterity to operate keyboard Frequently required to attend virtual meetings, listen, and talk Occasionally required to work additional hours to complete tasks, with compensatory time-off provided Travel Requirements Special conditions (e.g. lab/clinical requirements if applicable) EEO Statement: Baylor Genetics is proud to be an equal opportunity employer committed to fostering an inclusive and diverse workplace. We welcome and encourage applicants from all backgrounds to apply. We do not discriminate on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, age, veteran status, disability, genetic information, pregnancy, childbirth, or any other status protected by applicable federal, state, or local law. If you need an accommodation during the application process, please contact our Human Resources team. Qualifications Skills Preferred Oversight clinical testing & reporting Expert MS in Gen Counseling or PhD in Gen/Mol Bio Expert Expert-level clinical Gen knowl Expert Lead in process improv & workflow optim Expert Mentor & training of junior scientists Expert Adv clinical reporting & sci writing skills Expert Strong collab w/ clinicians, GCs, & bioinfo Expert Oversight of complex variant interp & case Expert Exp supporting quality initiatives & best Expert Ability to develop or refine SOPs & interp Expert Behaviors : Motivations : Education Preferred PHD or better in Molecular Cell Sciences.