Director, Portfolio Management - Remote US

It’s More Than a Career, It’s a Mission. Our people are the foundation of our success. By joining our growing team at Sarah Cannon Research Institute (SCRI), a subsidiary of McKesson, you will have the opportunity to become part of one of the largest community-based cancer programs to advance oncology treatments and improve outcomes for cancer patients across the globe. We look for mission-driven candidates who have a desire to advance the fight against cancer and make a difference in the lives of patients diagnosed with cancer every day. Our Mission People who live with cancer – those who work to prevent it, fight it, and survive it – are at the heart of every decision we make. Bringing the most innovative medical minds together with the most passionate caregivers in their communities, we are transforming care and personalizing treatment. Through clinical excellence and cutting-edge research, SCRI is redefining cancer care around the world. As Director, Portfolio Management , you will lead the strategy, execution, and success of a complex, multi‑study clinical research portfolio—playing a pivotal role in advancing clinical trials that matter. This is a senior leadership position for someone who thrives at the intersection of strategy, operations, and partnership and wants to make a visible impact on sponsors, teams, and patients. You will provide end‑to‑end portfolio leadership across the clinical trial lifecycle, ensuring consistent, high‑quality delivery while driving growth, innovation, and operational excellence. This is a fully remote position based in the US; relocation assistance and visa sponsorship are not available. What You’ll Lead Portfolio Strategy & Execution You will set the direction for a diverse clinical portfolio, translating strategic priorities into clear, executable plans. With oversight of scope, timelines, resourcing, quality, and financial performance, you’ll ensure strong governance, proactive risk management, and disciplined execution across studies. Sponsor Partnership & Portfolio Growth You’ll serve as a trusted senior partner to sponsors—leading governance, communications, and issue resolution while strengthening long‑term relationships. Working closely with investigators, cross‑functional leaders, and external partners, you’ll align priorities and drive successful outcomes. You will also collaborate with Business Development and Clinical Development teams to support proposals, expand partnerships, and grow the portfolio. Operational Excellence & People Leadership You’ll establish and sustain a strong operational rhythm that delivers visibility, accountability, and results. As owner of portfolio‑level KPIs, you’ll oversee financial performance, risk and issue escalation, and continuous improvement efforts. As a people leader, you’ll coach and develop high‑performing teams, foster talent growth, and serve as a key escalation point for complex delivery and client challenges. Why This Role Matters This role offers the opportunity to shape strategy, influence senior stakeholders, and lead teams through complex clinical programs—all while driving meaningful outcomes for sponsors and patients alike. If you are energized by leadership, accountability, and the challenge of delivering excellence at scale, this role puts you at the center of it. Qualifications Needed for Success: Bachelor’s Degree required, Master’s Degree preferred 7+ years’ experience in clinical research or project management including prior people leadership including line management Minimum 2 years’ experience in an Associate Director or equivalent role managing multiple complex clinical studies concurrently Demonstrated experience managing clinical trials independently Preferred Relevant Experience: 10+ years’ clinical research experience, Medical Affairs, including cross-functional engagement and evidence-generation support Pharma/CRO management experience Experience supporting Investigator-Initiated Trials (IITs) including feasibility, start-up coordination, oversight and stakeholder alignment. About Sarah Cannon Research Institute Sarah Cannon Research Institute (SCRI) is one of the world’s leading oncology research organizations conducting community-based clinical trials. Focused on advancing therapies for patients over the last three decades, SCRI is a leader in drug development. In 2022, SCRI formed a joint venture with former US Oncology Research to expand clinical trial access across the country. It has conducted more than 850 first-in-human clinical trials since its inception and contributed to pivotal research that has led to the majority of new cancer therapies approved by the FDA in the past decade. SCRI’s research network brings together more than 1,300 physicians who are enrolling patients into clinical trials at more than 200 locations in 20+ states across the U.S. Please click here to learn more about our research offerings. We care about the well-being of the patients and communities we serve, and that starts with caring for our people. That’s why we have a Total Rewards package that includes comprehensive benefits to support physical, mental, and financial well-being. Our Total Rewards offerings serve the different needs of our diverse colleague population and ensure they are the healthiest versions of themselves. For more information regarding benefits through our parent company, McKesson, please click here . As part of Total Rewards, we are proud to offer a competitive compensation package. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind: McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application. McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates. McKesson job postings are posted on our career site: careers.mckesson.com . We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.