"Expect to grow", personally and professionally: At Siegfried, we offer exciting challenges and ample opportunities to showcase your talents. As a trusted and respected partner to the pharmaceutical industry, we uphold the highest standards in safety, quality and sustainability, while fostering a culture that empowers you to thrive. Join a rapidly expanding global company, where diverse perspectives and experiences come together in a collaborative environment. Here, you'll find a workplace that values both collective success and your individual
contributions—offering
long-term opportunities to grow and make an impact.
Your Role:
Position Summary:
The (Sr.) Manufacturing Specialist DSP is responsible for executing viral vector manufacturing activities in a cGMP environment supporting gene therapy, cell therapy, and vaccine production. The role focuses on downstream processing operations, including chromatography, filtration, and purification, ensuring compliant batch execution and reliable delivery of high-quality products from clinical to commercial stages.
The position supports technology transfer, manufacturing readiness, troubleshooting, deviation management, and continuous improvement initiatives. Experience in Drug Product (DP) manufacturing, including aseptic processing and fill-finish operations, is an advantage.
Siegfried DINAMIQS is a Contract Development and Manufacturing Organization (CDMO) based in Schlieren-Zurich, Switzerland, specializing in the manufacturing of viral vector gene therapies. At DINAMIQS we offer a comprehensive range of services, including vector design optimization, cutting-edge process development and analytics, as well as manufacturing. With a R&D facility running and a newly constructed GMP facility, we are dedicated to supporting gene therapy projects with scalable and efficient solutions.
DINAMIQS became part of Siegfried's global network in 2023 and is now looking to grow its dedicated team of experts by hiring a Manufacturing Specialist / Sr. Manufacturing Specialist. If you are highly motivated, self-driven, and passionate about driving operational excellence in a dynamic environment, you are the person we are looking for.
- Execute DSP operations including chromatography, filtration, TFF, and UF/DF in a cGMP environment.
- Perform manufacturing activities according to batch records, SOPs, and GMP requirements.
- Prepare, operate, and maintain manufacturing equipment.
- Perform manufacturing support activities, including cleaning, monitoring, buffer preparation, material handling, and inventory management.
- Support technology transfer and process implementation into manufacturing.
- Troubleshoot process and equipment issues during manufacturing operations.
- Support deviation investigations, root cause analyses, and CAPA implementation.
- Ensure accurate and timely completion of GMP documentation and electronic systems (MES, LIMS, SAP).
- Contribute to continuous improvement and operational excellence initiatives.
- Collaborate with Quality, Engineering, Process Development, and Analytical teams.
Your Profile:
Bachelor's degree in Biology, Biotechnology, Biochemistry, Chemical Engineering, or a related scientific field with 3–6 years of relevant experience, ora Master's degree with 1–3 years of relevant experience. Equivalent combinations of education and experience may be considered.
Experience in biopharmaceutical, gene therapy, cell therapy, or viral vector manufacturing with a focus on DSP.
Hands-on experience with chromatography, filtration, and TFF/UF-DF operations.
Working knowledge of cGMP regulations, cleanroom operations, aseptic processing, and GMP documentation.
Experience with manufacturing systems such as MES, LIMS, or SAP is preferred.
Experience in Drug Product manufacturing (formulation, sterile filtration, aseptic fill-finish) is a plus.
Experience writing and maintaining SOPs and work instructions.
Strong troubleshooting, communication, and documentation skills.
Willingness to support flexible working hours, including weekends.
English speaking and writing, German is a plus.
Technical Skills
Viral vector purification processes (e.g., AAV, lentivirus, adenovirus).
DSP operations including chromatography, TFF, UF/DF, and filtration.
GMP batch execution, documentation, and electronic manufacturing systems.
Manufacturing process and equipment troubleshooting.
Knowledge of contamination control and aseptic manufacturing practices.
Soft Skills
Team-oriented with strong communication and collaboration skills.
Hands-on, proactive problem solver.
Able to perform effectively in a fast-paced GMP manufacturing environment.
High level of accountability, quality mindset, and attention to detail.
Your Benefits:
A unique and amazing work experience, being part of one of the most dynamic, diverse and inclusive CDMOs in the industry.
Competitive and attractive compensation
5 weeks holidays and flexible working hours make it possible to combine family, leisure time and career.
Impactful Work: Make a significant difference through innovative gene therapy projects
Learning Opportunities: Develop diverse skills in a dynamic environment
Fast-Paced Environment: See results quickly and enjoy the creative freedom from joining early in the facility lifecycle.
Founded in 1873 in Zofingen, Switzerland, Siegfried has grown into a global network of 16 sites across three continents. With a team of more than 4,200 highly skilled professionals, we take the innovations of our pharmaceutical customers to industrial scale and manufacture safe drugs for patients worldwide. As a fully integrated CDMO, Siegfried is one of the few organizations today that can carry out the development and manufacturing of APIs and finished dosage forms under one roof. This unique combination of know-how and experience makes us the most trusted partner in the pharmaceutical industry.