Remote | ADC & Bispecific Antibody R&D Scientist — $50–$90/hour

We are sharing a specialised part-time consulting opportunity for experienced preclinical R&D scientists with hands-on expertise in antibody-drug conjugates (ADCs), bispecific or multispecific antibodies, and in-house drug development. This role supports a research initiative focused on improving how advanced computational systems reason about real-world biologics discovery and preclinical development. Selected experts will review scientific materials and programme data, evaluate technical outputs, contribute practical judgement on modality and development decisions, and help define high-quality data structures grounded in authentic ADC and bispecific R&D workflows. Key Responsibilities ADC & Bispecific Programme Review Review technical materials and scientific data from ADC, bispecific, and multispecific antibody programmes Evaluate whether analyses and conclusions reflect realistic preclinical development practice Identify weak assumptions, unsupported claims, and biologically implausible outputs Apply hands-on programme experience to complex development scenarios Assess trade-offs involving efficacy, safety, developability, manufacturability, and programme risk Target & Modality Strategy Evaluate target-selection and modality-selection decisions Assess biological rationale, therapeutic hypothesis, and competitive differentiation Review trade-offs between ADC, bispecific, multispecific, and other biologic approaches Identify risks associated with target biology, expression patterns, mechanism of action, or therapeutic window Apply practical judgement to programme progression and prioritisation decisions ADC Development Contribute expertise across antibody selection, linker strategy, payload choice, conjugation, and overall ADC design Evaluate potency, selectivity, internalisation, stability, exposure, and toxicity considerations Review development decisions affecting efficacy and therapeutic index Assess preclinical evidence supporting candidate progression Identify common failure modes and optimisation challenges in ADC programmes Bispecific & Multispecific Antibodies Review programmes involving bispecific or multispecific antibody architectures Evaluate target combinations, binding strategy, format selection, and functional activity Assess developability, PK/PD, immunogenicity, safety, and manufacturability considerations Review translational evidence and candidate-selection decisions Identify modality-specific risks that may affect progression toward the clinic Preclinical & Translational Development Apply experience across in vitro, in vivo, translational, pharmacology, and PK/PD workflows Evaluate experimental design and interpretation of preclinical evidence Assess how findings influence candidate optimisation and development strategy Review programme readiness for lead optimisation or IND-enabling development Identify evidence gaps, unresolved risks, and appropriate next-stage studies Cross-Functional R&D Expertise Contribute expertise from areas such as: Discovery biology Medicinal chemistry Protein and antibody engineering Computational drug discovery In vivo and translational research Pharmacology and PK/PD Toxicology CMC and formulation Apply cross-functional judgement to integrated programme decisions Evaluate how findings from different disciplines affect candidate selection and development Scientific Data Evaluation Label, classify, and annotate scientific data and technical outputs Identify meaningful experimental signals, development decisions, and failure modes Evaluate the relevance and quality of information used in downstream research workflows Help establish consistent standards for scientific review and annotation Translate practical R&D expertise into structured, usable data Dataset & Research Development Help define structure and quality standards for scientific data pipelines Identify which experimental and development variables should be captured Surface workflow details that are often missed outside hands-on preclinical R&D Participate in expert discussions, interviews, and research engagements Provide practical perspective on how biologics programmes are advanced in industry Ideal Profile 5+ years of relevant pharmaceutical or biotechnology R&D experience , with flexibility for candidates demonstrating exceptional technical depth Hands-on, non-administrative preclinical R&D experience within a company developing its own therapeutic assets Direct professional experience with ADCs and/or bispecific or multispecific antibodies Experience at an organisation that has advanced internal drug programmes toward or into clinical development Current or recent work in a core R&D function such as discovery biology, medicinal chemistry, protein or antibody engineering, computational discovery, translational science, pharmacology, PK/PD, toxicology, or CMC Strong understanding of biologics discovery, optimisation, and preclinical development Experience advancing a programme through lead optimisation, IND-enabling studies, or preclinical development is highly valued Experience within mid-sized, emerging, or resource-constrained biotechnology environments is advantageous Seniority may range from experienced individual contributor through Director level Strong scientific judgement and ability to explain development decisions clearly This opportunity is best suited to hands-on drug-development professionals rather than backgrounds focused primarily on CRO/CDMO services, academic-only research, QC/analytical functions, clinical development, diagnostics, regulatory affairs, or medical writing Engagement Details Part-time independent contractor engagement Fully remote Expected commitment of approximately 10 hours per week Ongoing engagement based on project needs Compensation: $50–$90/hour Contributors will interact directly with the assigned research team Projects may be extended, shortened, or concluded based on project needs and performance Work must be completed without using confidential or proprietary information belonging to any employer, client, institution, or other third party H1-B and STEM OPT support is unavailable for this engagement About the Platform This opportunity is available through 24-MAG LLC. 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