Remote | Biology Research Scientist — $50–$90/hour

We are sharing a specialised part-time consulting opportunity for experienced biology research scientists with hands-on expertise in protein target validation, bioactivity assays, molecular pharmacology, and drug discovery research. This role focuses on verifying protein target assignments in large-scale bioactivity datasets using primary scientific literature and UniProt records. Selected scientists will investigate papers and patents, identify incorrect target mappings, propose corrected protein accessions, and document evidence-based scientific reasoning supporting each decision. Key Responsibilities Protein Target Validation Verify protein target assignments against primary scientific literature and UniProt records Determine whether assigned UniProt IDs accurately represent the proteins evaluated in underlying experiments Identify incorrect, ambiguous, or insufficiently supported target mappings Distinguish closely related proteins, isoforms, complexes, and target classes where relevant Apply scientific judgement to complex or incomplete experimental evidence Primary Literature Review Review peer-reviewed papers, patents, and related primary sources Extract relevant information about experimental targets, constructs, species, and assay conditions Trace bioactivity records back to their original experimental context Resolve discrepancies between database annotations and source publications Document findings using concise, evidence-grounded scientific notes Bioactivity & Assay Interpretation Interpret binding and functional assay results in the context of target identification Review data from techniques such as SPR, TR-FRET, radioligand binding, kinase assays, and GPCR functional assays Interpret quantitative measures including IC50, Ki, and KD Assess whether reported activity supports the assigned molecular target Recognise assay-specific limitations and sources of ambiguity Target Assignment & Error Classification Flag incorrect protein assignments using a structured error taxonomy Classify the nature of target-mapping errors consistently Propose corrected UniProt accessions where supported by available evidence Distinguish target-level annotation errors from broader experimental or database issues Maintain consistent standards across high-volume review workflows Drug Discovery Context Apply knowledge of target validation, biochemical profiling, and early drug discovery workflows Interpret protein-target evidence within SAR, HTS, selectivity, or IND-enabling contexts Evaluate agonist/antagonist and activator/inhibitor distinctions where relevant Consider selectivity and counterscreening evidence when assessing target assignments Connect experimental results with the intended biological mechanism Data Quality & Scientific Documentation Produce concise explanations supporting validation decisions Ensure conclusions are traceable to primary evidence Maintain accuracy and consistency across database review assignments Identify records requiring additional investigation or specialist judgement Support high-quality biological data used in downstream research workflows Ideal Profile Relevant professional background in pharmacology, biochemistry, molecular biology, chemical biology , or a closely related field One of the following experience profiles: BA/BS with 5+ years of relevant professional experience MS with 2+ years of relevant professional experience PhD with industry or drug-discovery research experience Relevant experience gained within a biotechnology company, pharmaceutical company, or CRO Currently active in a bench-based research scientist, scientist, or associate scientist role Hands-on experience with binding or functional assays such as SPR, TR-FRET, radioligand binding, kinase assays, or GPCR functional assays Strong understanding of bioactivity measures including IC50, Ki, and KD Working fluency with UniProt or closely related workflows such as SAR support, HTS, target validation, biochemical profiling, or IND-enabling studies Direct experience with ChEMBL, BindingDB, or PubChem is advantageous Selectivity profiling or counterscreening experience is advantageous Familiarity with agonist/antagonist versus activator/inhibitor distinctions is highly valued Strong scientific reading, interpretation, and evidence-documentation skills Must be based in the United States Engagement Details Part-time independent contractor engagement Fully remote within the United States Approximately 10–20 hours per week Compensation: $50–$90/hour Immediate start Initial commitment of approximately 1–2 months , with likely extension Work includes literature review, protein-target verification, UniProt mapping, error classification, and scientific documentation Projects may be extended, shortened, or concluded based on project needs and performance Work must be completed without using confidential or proprietary information belonging to any employer, client, institution, or other third party H1-B and STEM OPT support is unavailable for this engagement About the Platform This opportunity is available through 24-MAG LLC. 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