Lead HR Business Partner- US BioPharmaceuticals
- Hiring from
- United States
- Work type
- Hybrid
- Posted
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Lead HR Business Partner- US BioPharmaceuticals
Wilmington, DE
Human Resources
Hybrid Work- on average 3 days a week from office
The Lead HR Business Partner (HRBP) is a critical member of the US BioPharmaceuticals (US BBU) HR Leadership Team, accountable for shaping and delivering the people strategy that enables the Commercial business to achieve its ambitions. This role serves as a trusted advisor to senior leaders, translating business priorities into talent, organization, culture, and workforce strategies that drive sustainable performance.
The Lead HRBP has accountability for designing and implementing an integrated people strategy across an assigned client group, partnering closely with HR Centers of Excellence and HR colleagues to deliver exceptional employee and leadership experiences. The role combines strategic leadership, organizational effectiveness, talent development, workforce planning, change leadership, and coaching to ensure the business is equipped with the capabilities, leadership, and culture needed for future success.This role reports to the Vice President of HR, US BBU.
What you'll do
Contribute to the Commercial strategic workforce plan and the enterprise people and talent agenda through active participation on the US BBU HR Leadership Team.
Develop and execute an integrated people strategy aligned with the organization's vision, business priorities, and long-term objectives.
Serve as a trusted advisor to senior leaders, providing strategic counsel, challenge, and executive coaching to enhance leadership effectiveness and team performance.
Partner with HR Centers of Excellence to deliver effective and efficient solutions across talent management, rewards, performance, leadership development, employee experience, workforce planning, and recruitment.
Lead strategic talent reviews, succession planning, and leadership development efforts to build a strong and diverse pipeline of talent for current and future business needs.
Identify organizational capability gaps and design actionable organization, talent, and culture interventions that drive business performance.
Partner with leadership teams to shape organizational design, team effectiveness, and operating model decisions that support business transformation and growth.
Lead and support large-scale business change initiatives, ensuring thoughtful change management, stakeholder engagement, and adoption.
Use people analytics, workforce insights, and external trends to inform decision-making, identify opportunities, and measure the impact of HR strategies and interventions.
Apply foundational financial acumen including budgeting, FTE management, and facilitating demand planning activities to support the people agenda
Drive innovation and continuous improvement by leveraging digital technologies, AI, automation, and data-driven solutions to simplify processes, enhance the employee experience, improve decision-making, and create more efficient ways of working across the organization.
Essential for the role
Bachelor’s Degree in in Human Resources, Business, Psychology, or a related field
7+ years of HR experience within a large, sophisticated, and matrixed/global organization – preferably in HR client-facing role.
Digitally-savvy, with evidence of driving innovative solutions and a continuous improvement approach to HR implementation.
Demonstrable track record of leading the development and execution of HR and people strategies with measurable results.
Solid experience as a trusted advisor and coach to business leaders.
Excellent written and verbal communication skills, with the ability to influence, challenge, and negotiate at senior levels in an international environment.
Demonstrated use of HR analytics and organizational data to inform decision-making, develop interventions, and evaluate impact.
Desirable for the role
Master's degree
Project and change management experience
Leadership of teams and team effectiveness skills
Understanding of US employment law, policy, and risk management.
Office Working Requirements
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Date Posted
21-Oct-2026Closing Date
30-Oct-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
About Us
AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We
focus on discovering, developing and commercialising prescription medicines for some
of the world’s most serious diseases. But we are more than one of the world’s leading
pharmaceutical companies.
At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered
to push the boundaries of science, challenge convention and unleash your entrepreneurial
spirit. To embrace differences and take bold actions to drive the change needed to meet
global healthcare and sustainability challenges.
There is no better place to make a difference in medicine, patients, and society. An inclusive
culture where you will connect different thinking to generate new and valuable opportunities.
Where you will find a commitment to lifelong learning, growth and development for all.
Championing Inclusion and Diversity
Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients.
Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking.
Life at AstraZeneca
We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions.
As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential.
Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.
