Senior Director, Field Medical Affairs Team Lead

Senior Director, Field Medical Affairs Team Lead Remote (Eastern Time Hours) Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching the first curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases. The lead CARTA (Chimeric Antigen Receptor T cells for Autoimmunity) strategy is prioritizing the development of rese-cel, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. Rese-cel is currently being evaluated in the RESET™ (REstoring SElf-Tolerance) clinical development program spanning multiple therapeutic areas, including rheumatology, neurology and dermatology. Cabaletta Bio’s headquarters and labs are located in Philadelphia, PA. For more information, please visit www.cabalettabio.com and connect with us on LinkedIn. Uniquely Differentiated. Rapid. Elegant. At Cabaletta, we are driven by the shared mission of developing cures, where a patients’ own cells are used to fight disease. We are building a culture grounded in the knowledge that successful cures can be achieved for patients if every member of the Cabaletta is focused on the success of the team. To nurture this, we make an active commitment to the well-being and continuous growth of each employee who joins the team. In this way, we are not only working to improve the lives of patients, but of everyone involved. #CabalettaCrew. We’re proud to be a Great Place to Work-Certified™ company! #GPTWcertified Check out what our employees say makes working here so great: Working at Cabaletta Bio Inc | Great Place to Work® About the Position: We are seeking a highly motivated and experienced Senior Director, Field Medical Affairs Team Lead to lead the strategic development, build-out, and execution of the field medical organization in support of rese-cel in myositis and other autoimmune diseases. This leader will play a critical role in shaping field medical strategy, generating scientific insights, and establishing strong relationships with trial investigators, key opinion leaders (KOLs) and cell therapy treatment centers in a highly specialized and evolving therapeutic area. This position requires deep expertise in cell therapy, strong leadership capabilities, and experience in launching cellular therapies, including building teams, developing field strategies, and aligning cross-functional stakeholders. Responsibilities: Leadership & Team Development Build, lead, and mentor a high-performing MSL team aligned with pre-launch and launch objectives Establish team structure, hiring plans, onboarding, and training programs tailored to cell therapy complexities Foster a culture of scientific excellence, compliance, collaboration, and continuous learning Set performance expectations and ensure execution against strategic medical goals Medical Strategy & Execution Develop and implement the field medical strategy for rese-cel in alignment with medical and business plans Translate clinical and scientific data into impactful field engagement strategies Ensure readiness for launch, including scientific messaging, training materials, and KOL engagement plans Lead insight generation and ensure actionable feedback is integrated into broader medical and commercial strategies KOL & External Engagement Oversee strategic engagement with KOLs, investigators, and key cell therapy treatment centers Guide MSL team in delivering high-quality scientific exchange and managing complex clinical discussions Support advisory boards, investigator meetings, and scientific forums (including medical conferences) as appropriate Identify emerging thought leaders and key institutions in the cell therapy ecosystem Cross-Functional Collaboration Partner closely with Clinical Development, Clinical Operations, Commercial, Market Access, and Compliance Teams in order to achieve company objectives for clinical trial execution and pre-launch planning. Provide field insights to inform clinical trial design, evidence generation, and access strategies Support pre-launch planning, including disease state education and treatment pathway mapping Ensure alignment between field medical activities and broader organizational objectives Pre-Launch & Launch Readiness Participate in the development of launch readiness plans from a field medical affairs perspective Anticipate and address barriers related to cell therapy adoption (e.g., site readiness, logistics, safety concerns) Have an understanding of the national and regional healthcare and access environment Contribute to scientific narrative development and publication strategy Ensure compliance with all regulatory and legal requirements Operational Excellence Develop and manage budgets, KPIs, and reporting frameworks for the MSL organization Implement systems and tools to optimize field medical effectiveness Ensure adherence to compliance standards and company policies Monitor competitive landscape and evolving clinical data Qualifications: Advanced scientific degree (PharmD, PhD, MD, DO) with at least 10 years of experience in the pharma/biotech industry Minimum of 8 years’ experience as a Medical Science Liaison and 3-5 years leading a team of Medical Science Liaisons within the cell therapy space is required. Experience in cell therapy site certifications for commercialization is highly desirable. Therapeutic area expertise in immunology or autoimmune diseases is desirable but not required. Demonstrated ability to build and maintain relationships with internal and external stakeholders, fostering collaboration and alignment. Proven track record of developing and executing medical affairs strategies to support product development, launch, and lifecycle management Experience with developing and implementing KPIs for field engagement Expertise in the use of Customer Relationship Management tools (i.e. Veeva CRM) Excellent communication skills, with the ability to distill complex scientific concepts into clear, concise messages for KOLs and diverse audiences. Familiarity with regulatory requirements and ethical standards governing scientific research and development. Strategic thinking and problem-solving abilities, with a focus on driving innovation and achieving organizational objectives. Must be able to influence in a matrixed environment. Flexibility and adaptability to work in a dynamic, fast-paced environment, managing multiple projects simultaneously. Remote, field-based role with expected travel ~50% (mostly within US). Must be able to work Eastern Time hours, regardless of location. Our name – Cabaletta – is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long-term immunosuppression. For more information, please visit https://www.cabalettabio.com/join-our-crew Our most important asset is our people, and we offer competitive benefits, PTO, and stock option plans. Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Cabaletta Bio, Inc. does not accept unsolicited resumes from recruiters, employment agencies, or staffing firms. To conduct business with Cabaletta, a Master Services Agreement (MSA) must be executed and confirmed prior to submitting any information relating to a potential candidate. Without a signed MSA, Cabaletta shall not be responsible to any individual or entity for any payment relating to any form of fee or compensation. And, if a resume or candidate is submitted by a recruiter, an employment agency, or a staffing firm without a fully executed MSA, Cabaletta has the unrestricted right to pursue and hire any of those candidate(s) without any legal or financial responsibility to the recruiter, agency, and/or firm. #LI-REMOTE