Senior HR Business Partner

Location: London Reporting to: SVP, Head of Human Resources Job Summary Orchard Therapeutics is a global biotechnology gene therapy company dedicated to transforming the lives of people affected by rare diseases through the development of innovative, potentially curative cell and gene therapies. Orchard has its global headquarters in London and is a wholly owned subsidiary of Kyowa Kirin, a Japan-based Global Specialty Pharmaceutical Company. The Senior HR Business Partner (HRBP) is a critical strategic partner to C-level global functional leaders, providing expert advice, coaching and solutions across all aspects of the employee lifecycle. Reporting to the Head of HR, the HRBP will play a key role in shaping and importantly delivering people strategies that enhance organisational performance, capability and culture across a global, matrixed environment. Key Elements and Responsibilities: Partner with senior, C-level executive leadership and global functional leaders to provide strategic HR guidance across all aspects of the employee lifecycle, including talent, performance, engagement and organisational effectiveness Build trusted relationships and coach leaders to enhance capability, leadership effectiveness and organisational performance Act as a strategic partner in hiring, working with leaders and Talent Acquisition to define workforce needs, guide selection decisions and ensure high-quality, timely hiring outcomes Drive annual talent management processes, including goal setting, talent and succession reviews, performance management and compensation planning in collaboration with Global Rewards Develop and implement business-aligned HR strategies that support organisational goals, growth and transformation Contribute to the development of the HR function by coaching team members and supporting the Head of HR in building organisational capability Ensure effective utilisation and continuous improvement of HR systems, promoting data accuracy and insight-driven decision making Lead employee relations matters, ensuring appropriate handling, resolution and risk mitigation Monitor external trends and best practices to inform HR strategy and continuous improvement Ensure compliance with applicable employment legislation, policies and procedures Experience, skills and knowledge required: Significant global HR generalist experience, ideally within a complex, matrixed, international organisation Proven track record as an HRBP, influencing senior leaders to enhance organisational performance and drive change Strong business acumen, with the ability to influence executive and functional leadership on people-related matters in alignment with business priorities and performance outcomes Strong working knowledge of HR practices and employment frameworks across multiple geographies, with the ability to navigate regional nuances Demonstrated ability to build credible, trusted relationships and operate effectively at all organisational levels Skilled in coaching, influencing and constructively challenging leaders to enhance capability, engagement and performance Ability to translate business strategy into pragmatic, people-focused solutions and actions Strong analytical and problem-solving skills, with the ability to leverage data to inform decision-making Proficient in HR systems and technologies, with a focus on data integrity and continuous process improvement Highly organised with strong attention to detail and the ability to manage competing priorities Excellent communication skills, with the ability to convey complex information clearly and effectively Comfortable operating both strategically and hands-on in a fast-paced, evolving environment Experience within the biotechnology, biopharmaceutical or healthcare industry is preferred Education Bachelor’s degree (or equivalent) required, preferably in Human Resources, Business Administration or a related field, with a recognised professional HR qualification (e.g. CIPD or equivalent)