Senior Principal Scientist, Chem-Analytical
- Salary
- $124.4K–$207.4KUSD per year
- Moves you to
- United States
- Support
- Relocation support
- Posted
- Sep 29, 2026
Role Summary
Analytical Research & Development (ARD) is seeking a highly motivated digitally minded enablement and implementation lead to accelerate the deployment and adoption of digital technologies, automation solutions, artificial intelligence, and data-driven workflows across the across ARD activities and the development lifecycle. The role will bridge scientific teams, informatics, data engineering, AI strategy, laboratory operations, quality, and external partners to deliver scalable digital capabilities that improve ARD scientific productivity, data accessibility, laboratory efficiency, and decision-making. This role will be a key interface for ARD with our Pharmaceutical Sciences Transformational Technology organization and PSSM partner lines.
Key Responsibilities
- Lead implementation and enablement of ARD digital transformation initiatives aligned with ARD 2030 strategy and Digital Steering Team priorities.
- Identify, prioritize, and deploy automation, and digital solutions that improve scientific productivity and operational efficiency.
- Act as the primary liaison between ARD scientists and enterprise system owners (particularly CDS, ELN, LIMS, SDC and Snowflake), negotiating system designs that satisfy both innovation and compliance.
- Implement and scale digital laboratory solutions including digital documentation and workflow automation platforms in ARD.
- Utilize communication and networking skills to lead change in ARD with outstanding teamwork.
- Partner with scientists, informatics teams, data engineers, quality, regulatory, and business stakeholders to translate business needs into digital capabilities.
- Coordinate with Digital and PharmSci-Transformational Technology on project roadmaps, implementation plans, timelines, resources, dependencies, and success metrics.
- Support development of enterprise data strategies, data integration, knowledge management, FAIR data principles, standardized ontologies, and AI-ready data architectures.
- Identify opportunities to automate manual processes, reduce cycle times, improve data accessibility, and enhance data quality.
- Ensure digital solutions comply with GxP, data integrity, ALCOA+, cybersecurity, validation, and quality expectations.
- Coordinate with technology vendors and internal partners to evaluate, pilot, qualify, and deploy new digital capabilities.
- Develop change management, training, communication, and adoption strategies to maximize business impact.
- Serve as a digital champion and subject matter expert for emerging technologies within ARD.
- Foster a culture of innovation, continuous improvement, responsible AI use, and data-driven decision-making across the organization.
Education
- Bachelor’s degree in Chemistry, Analytical Chemistry, Chemical Engineering, Pharmaceutical Sciences, Data Science, Computer Science, Engineering, or a related scientific discipline with 10+ years of experience
- MS in Analytical Chemistry, Organic Chemistry, Engineering, or related discipline with 5+ years relevant experience.
Experience
- Minimum 12+ years of experience in pharmaceutical development, analytical R&D, manufacturing sciences, laboratory informatics, digital transformation, or a related area.
- Experience implementing digital technologies within regulated laboratories or pharmaceutical development environments.
- Demonstrated ability to lead cross-functional initiatives, influence stakeholders, and drive organizational change.
Technical Skills
- Familiarity with laboratory informatics systems such as LIMS, ELN, Empower, OpenLab, or related analytical data systems.
- Experience with digital laboratory execution platforms, workflow automation, digital forms, or electronic method execution.
- Exposure to laboratory automation, Smart Lab orchestration, robotics, or Process Analytical Technology environments.
- Understanding of enterprise data platforms such as Snowflake or cloud-based data environments.
- Working knowledge of Generative AI, Copilot-style tools, machine learning, analytics, or scientific knowledge management solutions.
- Ability to apply GxP, computerized system validation, data integrity, and quality expectations to digital solutions.
Preferred Qualifications
- Experience supporting analytical development, process development or PAT.
- Experience with BIOVIA OneLab, Veeva, OpenLab, OneFolio, Snowflake, Labware, or comparable enterprise platforms.
- Experience deploying AI, machine learning, knowledge graph, or advanced analytics solutions in scientific workflows.
- Experience leading Lab automation, digital workflow, or enterprise transformation programs.
- Certification or practical experience in Agile, PMP, Lean Six Sigma, design thinking, or equivalent implementation methodologies.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Work Location Assignment: Hybrid
The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.


Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.
Research and Development
About Us
A career at Pfizer offers opportunity, ownership and impact.
All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.