Exceptional system engineers sought to lead the development and management of systems infrastructure, software, and networks for a New York–based drug discovery and computational biochemistry research company. Successful hires will be responsible for managing the teams that develop and maintain our compute clusters and software environment, including:

Linux fleet with over a hundred thousand CPU cores running Slurm and Kubernetes
State-of-the-art GPU clusters with thousands of GPUs
Tens of petabytes of storage
High-performance RDMA fabrics and wide-area networks
Public cloud environments
Large-scale scientific workflows to support our drug discovery research efforts
Massively parallel custom supercomputers
Making all of the above available to researchers in a secure and convenient way

Ideal candidates will have strong fundamental knowledge of Linux concepts such as file systems, networking, and processes in addition to practical experience administering Linux systems. Relevant areas of expertise might include large-installation systems administration, HPC systems engineering, programming and scripting of distributed systems in Python, high performance data-parallel computing, systems software, software development, and deployment of security tools, but specific knowledge of and level of experience in any of these areas is less critical than intellectual curiosity, versatility, and a track record of achievement. Candidates should have excellent communication skills, and at least five years of experience is preferred. Experience leading and managing teams is a plus but not required. This role would be located in either our New York City offices or in our Durham, NC and Pittsburgh, PA data centers.

We are looking to add innovative contributors who share our commitment to fostering a stimulating, positive, and collaborative work environment.

D. E. Shaw Research (DESRES) develops and uses advanced computational technologies to understand the behavior of biologically and pharmaceutically significant molecules at an atomic level of detail, and to design precisely targeted, highly selective drugs for the treatment of various diseases. Among its core technologies is Anton, a proprietary special-purpose supercomputer that DESRES designed and constructed to vastly accelerate the process of molecular dynamics simulation. DESRES uses Anton machines and high-speed commodity hardware, together with machine learning methods and other computational techniques, in both internal and collaborative drug discovery programs. For more information, visit www.DEShawResearch.com.

To submit an application, please use the link provided below:

https://apply.deshawresearch.com/careers/Register?pipelineId=976&source=LinkedIn

The expected annual base salary for this position is $400,000–$1,000,000. Our compensation package also includes variable compensation in the form of sign-on and year-end bonuses, and generous benefits, including relocation and immigration assistance. The applicable annual base salary paid to a successful applicant will be determined based on multiple factors including the

nature and extent of prior experience, educational background, and location. We follow a hybrid work schedule, in which employees work from the office three days per week, and have the option of working from home the other two days per week.

D. E. Shaw Research, LLC is an equal opportunity employer.

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