Accounting Manager

Job Title: Manager/Senior Manager Accounting Location: San Francisco, CA (hybrid) Position Type: Full Time Reports to: VP, Corporate Controller Position Summary Latigo Biotherapeutics is seeking a hands-on Accounting Manager or Senior Accounting Manager to manage the monthly and quarterly close, prepare accrual entries and reconciliations, and provide a strong review layer across general accounting areas. This individual exercises sound judgment, takes ownership of outcomes, and is highly motivated to consistently deliver high-quality results while supporting the growth and scalability of the organization. The role will partner closely with the Assistant Controller and cross-functional teams to support an accurate and scalable accounting function. The title and level will be determined based on experience. At Latigo’s accounting team, it is all about teamwork. A successful candidate thrives in a fast-paced environment and is proactive, highly organized, results-oriented, and analytical, with strong attention to detail and excellent communication skills. Key Responsibilities Manage the month-end and quarter-end close, including the close calendar, checklist, priorities, and open items. Own complex accounting areas relevant to biotech, accruals, payroll and benefits, stock-based compensation, investments, leases and prepaids. Identify and escalate emerging accounting risks in a timely manner and recommend appropriate accounting positions Review journal entries, reconciliations, flux analyses, and close support prepared by the accounting team. Take ownership of general accounting areas, including G&A accruals, prepaids, cash, fixed assets, and bonus accruals. Review assigned CMC and other R&D accruals. Review payroll and equity accounting entries and reconciliations. Coordinate audit requests and support SOX activities for applicable areas. Identify control gaps and implement remediation plans Help develop accounting policies, procedures, and documentation Lead process improvement initiatives to increase efficiency, reduce manual work, and enhance data quality Collaborate with SEC reporting function. Own sections of the quarterly and annual SEC filings (10-Q, 10-K), including preparation and review of footnote disclosure Manage, coach, and lead future direct reports. Provide mentorship and career development opportunities, fostering a culture of excellence and continuous learning Qualifications Bachelor's degree in accounting, Finance, or a related field; CPA required. 6+ years of progressive accounting experience, including close ownership and review of accounting work. Strong knowledge of U.S. GAAP, accrual accounting, journal entries, reconciliations, and financial statement support. Biotechnology, life sciences, or clinical accrual experience is strongly preferred. Big4 experience with SEC-registered clients and industry experience preferred Experience partnering with Clinical Operations and FP&A on clinical trial accruals is preferred. Payroll accounting, equity accounting, audit, SOX, and systems implementation experience are beneficial. Experience with NetSuite, Prendio, FloQast, Coupa, TriNet, Excel, workflow automation, or AI-enabled tools is a plus. AP processing experience preferred Ability to identify opportunities where AI can add value, evaluate potential risks or limitations, and implement solutions effectively. Ability to communicate (orally and in writing) professionally when dealing with company leadership, employees and vendors.