Clinical Research Associate II

CRA II - United Kingdom

Remote | Global CRO | Flexible Monitoring Model | Career Development Focus

Looking for a CRA role that genuinely supports work-life balance while investing in your long-term career?

We're supporting a leading global CRO in their search for a CRA II to join their UK Clinical Operations team.

This organisation has built a strong reputation for developing its CRAs and creating sustainable workloads. Rather than focusing on monitoring volume, study oversight is driven by quality, risk assessment and site requirements.

What Makes This Different?

Many CRA roles promise flexibility, but few move away from traditional site visit metrics.

This organisation takes a more intelligent approach, using risk-based monitoring principles to determine visit frequency, meaning you'll spend more time adding value and less time travelling for unnecessary visits.

You'll also benefit from a dedicated buddy and mentor from day one, extensive development programmes and clear progression opportunities into Senior CRA, Clinical Trial Management and wider Clinical Operations roles.

The business supports both FSP and multi-sponsor studies, providing valuable exposure to different operating models and therapeutic areas throughout your career.

Why Join?

• Remote-based position
• Regional site allocation where possible
• No fixed site visit quotas
• Dedicated mentor and buddy support
• Structured training and development programme
• Exposure to both FSP and multi-sponsor environments
• Clear progression opportunities
• Comprehensive healthcare and insurance benefits
• Home office support package

Key Responsibilities

• Conduct qualification, site selection, initiation, routine monitoring and close-out visits across assigned studies.
• Perform comprehensive source data verification (SDV) and source data review (SDR) activities to ensure data quality and patient safety.
• Evaluate site performance, protocol compliance and overall study conduct.
• Identify, investigate and escalate quality issues, protocol deviations and site risks appropriately.
• Review informed consent processes and ensure patient protection procedures are maintained.
• Verify investigational product accountability, storage requirements and site documentation.
• Ensure investigator site files remain inspection-ready throughout the study lifecycle.
• Support sites with recruitment, retention and study execution strategies.
• Review electronic CRFs and collaborate with sites to resolve data queries efficiently.
• Produce high-quality monitoring reports and follow-up correspondence within required timelines.
• Build effective working relationships with investigators, study coordinators and key opinion leaders.
• Participate in investigator meetings, project meetings and sponsor governance discussions.
• Support audit and inspection readiness activities.
• Share best practice across study teams and provide mentorship and guidance to junior CRAs where appropriate.

Experience & Requirements

• Previous independent on-site monitoring experience.
• Experience conducting monitoring visits in accordance with ICH-GCP requirements.
• Understanding of the clinical trial lifecycle from site activation through close-out.
• Experience reviewing source documentation and resolving data queries.
• Knowledge of protocol compliance and regulatory requirements.
• Strong communication and relationship-building skills.
• Oncology experience advantageous but not required.
• Ability to travel throughout the UK as required.