Clinical Research Manager (CRM)

Job Description

The Clinical Research Manager (CRM) is responsible for ensuring the successful execution of assigned clinical studies at the country level, from study start-up through close-out.

The CRM coordinates investigators, clinical research sites, vendors, Clinical Research Associates (CRAs), and internal cross-functional teams to ensure studies are delivered in accordance with agreed timelines, quality standards, study protocols, Good Clinical Practice (GCP), and applicable regulatory requirements.

This role serves as a key connection between local clinical operations and global study teams, proactively managing risks, resolving operational challenges, and driving effective study execution.

Key Responsibilities:

• Lead and oversee the operational execution of assigned clinical studies.
• Ensure study activities are delivered in accordance with timelines, quality expectations, protocols, GCP, and applicable local regulatory requirements.
• Coordinate and collaborate with investigators, research sites, CRAs, vendors, and internal study teams.
• Monitor study performance through clinical systems, dashboards, metrics, and data-driven insights.
• Proactively identify operational, regulatory, quality, financial, or timeline risks and implement appropriate mitigation plans.
• Exercise sound judgment and make decisions within the scope of assigned responsibilities, escalating issues when appropriate.
• Support sites and study teams in addressing operational challenges, including patient recruitment, site performance, resource constraints, compliance matters, and stakeholder alignment.
• Build strong relationships across local, regional, and global teams and effectively influence stakeholders without direct authority.
• Support the adoption of new processes, technologies, digital solutions, and evolving ways of working.
• Contribute to continuous improvement initiatives across Clinical Operations.

Required Qualifications:

• Bachelor's degree in Life Sciences, Health Sciences, or a related field.
• More than 6 years of relevant experience in clinical research.
• Previous experience as a Clinical Research Associate is strongly preferred, ideally including at least 3 years of clinical monitoring experience.
• Oncology Experience is preferred.
• Advanced English proficiency, with the ability to communicate effectively in a global and cross-functional environment.
• Strong knowledge of clinical research operations, Good Clinical Practice (GCP), and applicable local regulations.
• Demonstrated experience working effectively with investigators, clinical research sites, vendors, and cross-functional teams.
• Travel: 20%-30% locally & internationally.

The ability to build trusted relationships, influence outcomes, negotiate effectively, and navigate complex stakeholder environments is critical to success in this role.

Key Capabilities

Accountability & Decision Making

• Takes ownership of outcomes for assigned clinical studies.
• Demonstrates autonomy and sound judgment within the scope of responsibility.
• Effectively determines when issues should be resolved independently and when escalation is required.

Digital & Data Proficiency

• Effectively uses clinical systems, dashboards, performance metrics, and data to manage study execution.
• Leverages insights to anticipate risks, identify trends, and support informed decision-making.
• Demonstrates curiosity and openness toward automation, digital solutions, and company-approved AI-enabled tools.

Change Management

• Actively contributes to and supports change initiatives.
• Facilitates adoption of new tools, processes, and ways of working.
• Supports colleagues and stakeholders in successfully navigating change.

Critical Thinking

• Evaluates complex issues from multiple perspectives.
• Assesses risks, implications, and trade-offs before making decisions.
• Develops pragmatic solutions that balance operational, regulatory, quality, and business considerations.

Agile & Flexible Mindset

• Adapts effectively to evolving study priorities and business needs.
• Operates successfully in dynamic, global, cross-functional, and virtual environments.
• Demonstrates resilience and flexibility when managing ambiguity or unexpected challenges.

Risk-Based Decision Making & Leadership

• Proactively identifies operational, regulatory, quality, financial, and timeline-related risks.
• Prioritizes actions based on potential impact to the study, patients, sites, and business.
• Applies a structured, risk-based approach to decision-making and problem-solving.

Relationship & Stakeholder Management

• Builds strong and trusted relationships with investigators, clinical sites, vendors, and internal stakeholders.
• Influences effectively without relying on formal authority.
• Navigates complex negotiations, competing priorities, and conflict constructively.
• Demonstrates empathy, diplomacy, and strong written and verbal communication skills.

Additional location(s) Compensation Information:

Required Skills:

Preferred Skills:

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Relocation:

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Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century. Our success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

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