Controller

Who We Are:

Osanni is a development-stage therapeutics platform, headquartered in San Francisco, California. We are creative and agile innovators, relentlessly curious about finding new ways to target the biology behind diseases with the greatest unmet need and determined to do something about it.

At the center of Osanni is its innovation engine, which is optimized for discovering new scientific insights, designing novel drug concepts, and efficiently advancing programs to a meaningful proof-of-concept. Once a program is sufficiently de-risked, it graduates into its ecosystem of affiliate companies (called Avians), which are equipped with the dedicated focus, specialized talent and support necessary to scale. Osanni's architecture marries the scientific depth and operational power of a centralized platform with the speed, agility and accountability of independent companies. The result: an opportunity to create and deliver more transformative medicines.

We hold patients and the physicians who care for them as our North Star. It guides our purpose, sharpens our decision-making, and defines our impact. Osanni is currently advancing programs in ophthalmology, cardiology and beyond. We are building a highly skilled team, passionate about having an impact on human health. Be part of creating an organization where people enjoy their work and their colleagues, are valued for their individuality, and can't imagine working anywhere else.

This role is based in the San Francisco Bay Area and requires working on-site 3 days/week.

About the Role

The Controller is responsible for leading Osanni's accounting operations across the hub and its Avians, owning the close, consolidation, internal controls, audit, and technical accounting that give leadership an accurate, timely view of each entity's financial position. Reporting to the CFO, this role builds the multi-entity accounting infrastructure that allows our hub-and-Avian model to scale as new Avians are formed, financed, and partnered. As Osanni grows, the Controller will be a key partner to the CFO, FP&A, and functional leaders in supporting financings, business development, and sound capital allocation decisions.

The ideal candidate brings strong technical accounting judgment paired with a builder's mindset, comfortable designing scalable processes and rolling up their sleeves to execute them. They hold themselves to a high standard of accuracy and integrity, and they thrive in ambiguity, adapting quickly as priorities shift in a fast-paced, evolving biotech environment. A collaborative communicator, they translate complex financial information into clear insights for scientific, operational, and executive partners across the organization.

What You Will Do

• Lead the monthly, quarterly, and annual close for Osanni and its Avians, delivering accurate, timely consolidated financial statements in accordance with U.S. GAAP.
• Build and maintain the accounting infrastructure for the hub-and-Avian model, including entity structure, chart of accounts, intercompany agreements, cost allocations, shared-services charge-backs, and consolidation with clean eliminations and reconciliations across all entities.
• Partner with the CFO and Sr. Director, FP&A on budgeting, forecasting, and cash planning at both the hub and Avian level, providing analysis that supports capital allocation and program decisions.
• Design, document, and maintain internal controls and accounting policies that scale as new Avians are formed, financed, or partnered.
• Own the annual financial statement audit, quarterly reviews, and Avian-level audits as the primary point of contact for external auditors, preparing audit-ready schedules and documentation, managing PBC timelines, and resolving findings promptly to support financings, partnerships, and future public-company readiness.
• Oversee technical accounting for complex areas such as R&D accruals, equity and stock-based compensation, convertible instruments, licensing and collaboration agreements, and leases (ASC 842).
• Partner with People & Culture on payroll, benefits, and equity administration, and with Clinical, CMC, and R&D leaders on CRO/CDMO contracts, accruals, and vendor spend.
• Coordinate with outside tax advisors on federal, state, and R&D credit filings, 409A valuations, and the tax implications of new Avian structures and transactions.
• Support financings, Avian formation, business development, and diligence activities by preparing financial data, entity-level reporting, and investor and board materials.
• Select, implement, and optimize finance systems (ERP, AP automation, expense management) that support efficient multi-entity operations.
• Manage multiple priorities in a fast-paced, evolving environment, ensuring deliverables are completed accurately and on time, while performing other related duties as required.

What You Bring

• Bachelor's degree in Accounting or Finance required; active CPA license strongly preferred.
• Minimum of 12 years of progressive accounting experience, with at least 5 years as a Controller or Assistant Controller; prior public accounting experience preferred.
• Experience in a biotech, pharma, or life sciences company, including working knowledge of R&D accruals, CRO/CDMO contracts, and collaboration or licensing accounting, as well as support for financings, diligence, and new entity formation.
• Knowledge of U.S. GAAP and proven experience with multi-entity accounting, intercompany transactions, and consolidations; hub-and-spoke, subsidiary, or M&A experience preferred.
• Track record of managing successful external audits, building scalable internal controls, and implementing or optimizing multi-entity ERP and finance systems (e.g., NetSuite, Sage Intacct); advanced Excel skills.
• Demonstrated ability to build, lead, and develop a high-performing accounting team, including managing outsourced accounting partners.
• Strong communication skills, high integrity, and attention to detail, with the ability to explain complex accounting matters clearly to non-finance partners, auditors, and the board, paired with a collaborative, hands-on, and adaptable working style.