Executive Director, Global Supply Chain

Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. Deciphera is leveraging its proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines. In addition to advancing multiple product candidates from Deciphera’s platform in clinical studies, QINLOCK® (ripretinib) is Deciphera’s switch-control kinase inhibitor approved in many countries including the European Union and the United States for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib. ROMVIMZA® (vimseltinib) is a kinase inhibitor approved in the United States for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity, and in the European Union for adult patients with TGCT associated with clinically relevant physical function deterioration and in whom surgical options have been exhausted or would induce unacceptable morbidity or disability.

The spirit of collaboration that has brought medications to life continues to guide how we operate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability, empowering individuals to challenge the unknown together.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

Deciphera is seeking an Executive Director, Global Supply Chain to lead our global clinical and commercial supply chain organization.

You'll be responsible for ensuring reliable product supply across our portfolio, guiding critical supply decisions, leading a high-performing team, and partnering closely with stakeholders across Deciphera and ONO.

This role is ideal for a seasoned biotech supply chain leader with deep clinical supply expertise, commercial launch experience, and the ability to step into a highly visible leadership role with immediate impact.

What You'll Do

• Lead Deciphera's global clinical and commercial supply chain strategy and execution across the product lifecycle.

• Ensure uninterrupted supply across clinical studies, commercial operations, and future product launches.

• Member of the leadership team, this includes budgeting, forecasting and S&OP

• Partner with Technical Operations, Clinical Operations, Quality, Regulatory, Commercial, Finance, and ONO colleagues to drive critical supply decisions and manage risk.

• Lead and develop a high-performing global supply chain organization.

• Oversee key external manufacturing, packaging, logistics, and distribution partners.

• Guide inventory, capacity, demand planning, and supply continuity strategies in support of business objectives.

What We're Looking For

• Deep clinical supply chain leadership experience supporting global Phase I-III programs.

• Commercial supply experience, including at least one successful product launch and support of marketed products.

• Executive leadership experience with the ability to lead leaders, influence decisions, navigate complex stakeholder environments, and drive results through others rather than direct execution.

• Experience leading end-to-end supply chain strategy and operations from clinical development through commercialization.

• Proven success managing outsourced manufacturing and global supply networks, including CMO/CDMO partnerships.

• Executive presence and the ability to effectively partner with senior leadership, cross-functional stakeholders, and global colleagues.

• 15+ years of progressive supply chain experience within biotechnology or pharmaceuticals.

• Ability to step into a highly visible leadership role with minimal ramp-up time and quickly become a trusted business partner.

Preferred Qualifications

• Experience supporting multiple global product launches.

• Experience within a highly outsourced biotechnology operating model.

• Experience partnering with international stakeholders and global leadership teams.

• Advanced degree and/or APICS certification.

Location: This is a Hybrid position located in Waltham MA

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $243,900 - $335,300. Actual compensation packages will depend on various factors, including but not limited to depth of experience, education, skillset, overall performance, and location.

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera's competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, a full range of benefits, and other incentive compensation plans (if applicable).

Benefits

• Competitive salary and annual bonus
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more
• Generous parental leave and family planning benefits
• Outstanding culture and opportunities for personal and professional growth

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to making all hiring decisions and other employment decisions on a non-discriminatory basis.

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.