Principal Scientist DDSAI AI/ML
- Salary
- $117K–$201.3KUSD
- Hiring from
- United States
- Work type
- Hybrid
- Posted
- Oct 2, 2026
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com
As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.
Job Function:
Data Analytics & Computational SciencesJob Sub Function:
Data ScienceJob Category:
Scientific/TechnologyAll Job Posting Locations:
Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of AmericaJob Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at https://www.jnj.com/innovative-medicine
This is a hybrid role available in multiple locations within Raritan, New Jersey; Spring House, Pennsylvania; and Cambridge, Massachusetts. While specific cities are listed in the Locations section for reference, please note that they are examples only and do not limit your application. We invite candidates from various locations to apply and encourage you to review the following states/cities where this opportunity is available:
Raritan, New Jersey
Spring House, Pennsylvania
Cambridge, Massachusetts
An internal pre-identified candidate for consideration has been identified. However, all applications will be considered.
We are searching for the best talent for the Principal Scientist position.
Purpose: Serves as an individual contributor who is a developing subject matter expert in the Data Science field. Develops actionable insights for methods and research for the internal Data Science community. Applies in-depth skills of the field to design and develop industry-leading products. Contributes to scientific projects, programs, and processes of importance to the organization's Data Science function.
Key Responsibilities:
- Develop and benchmark novel agent architectures, reasoning strategies, and tool-use patterns — determining how LLM-based agents can autonomously plan, hypothesize, and execute within scientific research workflows.
- Prototype agentic capabilities as proof-of-concepts across therapeutic areas (drug discovery, clinical development, translational science), rapidly iterating to identify which approaches deliver genuine scientific value versus incremental automation.
- Partner with therapeutic-area researchers to identify high-impact research problems where agentic AI can change what's feasible — translating domain expertise into concrete agent designs and experimental tool integrations.
- Publish findings through peer-reviewed papers, demonstrations, and knowledge-sharing that advances J&J's scientific position in agentic AI and attract top research talent.
- Establish the patterns and reference implementations that allow successful innovations to graduate from experimentation into the broader platform — defining what 'ready for production' looks like without owning ongoing operations.
Preferred ("nice-to-have") qualifications:
- Familiarity with scientific data types, biomedical ontologies, or research workflows in drug discovery, clinical development, or translational science.
- Experience designing and running benchmarks or evaluation harnesses for AI agent performance in scientific domains.
- Track record of technical mentorship and cross-team scientific leadership — helping others adopt and extend novel AI capabilities.
- Experience with cloud-native infrastructure, containerized deployment (e.g., Kubernetes), CI/CD pipelines, and agile development practices — sufficient to move prototypes toward production-ready services.
Qualifications/Requirements:
- Master's degree or ain Computer Science, Data Science, Computational Biology, or a related discipline.
- Proven experience designing, building, and evaluating AI/ML systems or scientific software — with a track record of moving from research prototype to demonstrated impact.
- Strong proficiency in Python and scientific computing; comfort with rapid prototyping, experimental design, and rigorous evaluation of AI capabilities.
- Hands-on experience with LLM-based systems and frameworks (e.g., LangChain, LangFuse, etc.) used for agent orchestration, tool-calling, prompt engineering, retrieval augmented generation, and/or evaluation frameworks.
- Ability to work independently and within distributed developer teams utilizing agile programming methodologies
- Ability to collaborate across disciplines — translating between therapeutic area scientists, data scientists, and engineers to turn domain problems into concrete agentic AI solutions.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.
If you are under 18 years of age you (the candidate) may need to obtain the necessary working papers or other documentation required by state law to start the assignment, as well as get a parent’s consent for the background check
Required Skills:
Preferred Skills:
Advanced Analytics, Coaching, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Organizing, Process Improvements, Strategic Thinking, Technical Credibility, Workflow AnalysisThe anticipated base pay range for this position is :
$117,000.00 - $201,250.00Additional Description for Pay Transparency:
Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).This position is eligible to participate in the Company’s long-term incentive program.
Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:
Vacation –120 hours per calendar year
Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
Holiday pay, including Floating Holidays –13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period10 days
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year
For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits
About Us
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.