Principal Talent Acquisition

Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

Principal Partner, Talent Acquisition is a key member of the Human Resources team and is responsible for driving the recruitment process to attract and hire top talent at all levels. This is a remote position with occasional travel required. Reporting to the Director of Talent Acquisition, this role requires a strategic and hands-on approach to sourcing, assessing, hiring and onboarding candidates.

Key Accountabilities/Core Job Responsibilities:

• Design and execute full cycle recruitment strategies

• Manage requisitions, sourcing, screening, and hiring processes

• Partner with Business Leaders and HR colleagues to anticipate and prioritize hiring for current and future organizational needs

• Direct sourcing for a variety of skill sets and levels to include individual contributor through executive

• Assess and proactively source for complex, high-impact searches, including executive roles, utilizing a multitude of channels to identify and attract talent

• Design structured interview plans and coach hiring managers on effective, consistent interviewing practices

• Consult and guide hiring managers on candidate assessments and hiring decisions

• Develop competitive offers in partnership with HR Leadership, and present and negotiate offers with candidates through acceptance

• Partner with employment counsel to support immigration and visa sponsorship as needed

• Coordinate a seamless handoff to HR to ensure a smooth onboarding experience for new hires

• Communicate consistently and proactively throughout the recruitment process to ensure all participants are updated and well informed

• Partner with Hiring Managers and internal stakeholders to ensure every candidate has an exemplary experience throughout their recruitment journey

• Proactively gather and share market insights and competitive intelligence to inform direction of searches and to identify targeted talent pools

• Ensure all recruiting activities comply with applicable employment laws, regulations, and company policies

• Lead Talent Acquisition projects and initiatives, often cross-functional, that strengthen the recruiting function and advance recruiting practices

• Serve as a trusted advisor and source of recruiting expertise to hiring managers and HR colleagues

Qualifications/Skills:

• Typically requires a minimum of 12 years of related experience with a bachelor’s degree, or 10 years with a master’s degree, or equivalent experience, recruiting in a fast paced and dynamic environment (biotech or pharma required)

• Full lifecycle recruiting experience is a must

• Exceptional stakeholder management skills to include partnering, consulting and influencing

• Proven experience attracting, engaging and influencing passive talent across all skill sets, including executive level talent

• Demonstrated experience developing, presenting, and negotiating offers, including at the executive level

• Strong communication, collaboration, time management and decision-making skills are required

• Ability to build strong relationships and manage expectations with candidates and business stakeholders

• Experience using data (talent analytics, market insights and competitive intelligence) to inform business stakeholders and search strategies

• Experience using AI in a variety of ways to source, review candidates and streamline the interview process

• Experience using ATS technologies; Workday experience is a plus

• Familiarity with immigration and visa sponsorship processes is a plus

• Ability to travel as needed for key meetings and company events

Salary Range: $159,000.00 to $207,000.00 . Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers

This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Life at Denali

“Life at Denali” is a living reflection of our values: trust, unity, grit and growth. These are not just words we share—they shape how we show up, collaborate and push boundaries together. From the lab to the community, across functions and milestones, our culture thrives on shared purpose and relentless pursuit.