Quality Control Analyst, Operations Co-Op (Spring 2027)

Our Opportunity...

We are looking for a for a detail oriented, flexible, collaborative, and dynamic Co-Op to join our Quality Control Team. You will assist with Quality Control projects related to our cell therapy (TIL) manufacturing activities. You will contribute to maintaining trending spreadsheets, data verification and overall tracking of QC data and documents. You’ll be a vital part of a highly collaborative team working to achieve Obsidian’s vision by translating innovative science into medical breakthroughs for patients, starting with our lead program cytoTIL15 engineered to make TILs more effective for more patients.

As a member of our Quality Control Department, you will be a vital part of a highly collaborative group working to unlock the promise of precision cell therapy for patients, starting with our lead program amsoki-cel (OBX-115), a novel engineered tumor-infiltrating lymphocyte (TIL) cell therapy that uses our proprietary cytoDRiVE® platform. This is a unique opportunity to be a valuable contributor in a well-funded clinical company with field-leading advisors, best-in-class partners, and an experienced team.

This is a Hybrid role that will begin on-site in Cambridge, MA and transition to Bedford, MA in March 2027 as Obsidian consolidates operations into its expanded headquarters. Candidates must be able to work from both locations during the semester.

• This role does not include a laboratory-based component

Work Outcomes...

• Accurate QC Data Tracking and Trending
  The co-op will maintain spreadsheets used to track cell therapy, viral vector, and ancillary material QC data. This work will help the team identify trends, monitor testing status, and keep critical quality information organized.
• QC Document and Timeline Tracking
  You will track incoming data, QC documents, and testing timelines to support visibility into project progress and upcoming deliverables. This will help the team stay aligned and reduce potential delays.
• Data and Report Verification
  You will review QC reports, tracking sheets, and supporting documents for accuracy, completeness, and consistency. Your work will strengthen data integrity and support reliable quality decisions.
• Team Updates and Project Support
  You will summarize and communicate QC updates during team meetings and contribute to ongoing projects. This will improve cross-functional coordination and help the QC team manage competing priorities.
• Support for Cell Therapy Program Goals By improving the organization, accuracy, and availability of QC information, you will support timely testing and manufacturing activities. Your contributions will help the company advance its cell therapy programs and ultimately support the delivery of therapies to patients.

Learning Outcomes...

• Develop a foundational understanding of QC activities, testing methods and quality requirements
• Gain hands on experience using Excel and tracking spreadsheets to enter, organize, trend and monitor QC data, documents and testing timelines.
• Learn how to communicate QC updates and results during team meetings.
• Build attention to detail by verifying QC reports, tracking sheets and supporting documents for accuracy, completeness and consistency

You Will...

Core responsibilities

• Assist with tracking cell therapy, viral vector, ancillary materials quality control data including data entry into spreadsheets.
• Track documents, incoming data, and relative QC timelines as well as
• Conduct data verification of reports and various QC Tracking sheets and documents.
• Learn about Cell Therapy manufacturing and QC testing
• Learn how to effectively use tracking spreadsheets. communicate results in team meetings and navigate a fast-paced biotech environment.
• Make intellectual and technical contributions to projects, while working on a collaborative team.

You Bring...

Core Qualifications

• Working towards the completion of a Master’s degree in Bioengineering Cell and Molecular Biology, Biology, Biochemistry, Immunology, or other related major.
• Experience using Excel spreadsheets.
• An interested in learning about Quality Control in cell therapy manufacturing.
• High level of motivation and ability to work both independently and collaboratively.
• Adaptability, scientific curiosity, and desire to learn new skills.
• Excellent organizational skill and attention to detail as applied to record-keeping.
• Attention to detail as applied to record-keeping.
• Self-motivated, with a proven ability to meet objectives, timelines, and high standards managing multiple responsibilities in parallel.
• Flexible - adapts to change in a fast paced, rapidly developing environment
• Curious and humble – seeks and welcomes input/expertise of others, continuous learner
• Tenacious and resilient – is not easily overwhelmed by challenges, delivers on commitments, operates with urgency.
• Self-motivated, with a proven ability to meet objectives, timelines, and high standards managing multiple responsibilities in parallel.
• Flexible - adapts to change in a fast paced, rapidly developing environment
• Curious and humble – seeks and welcomes input/expertise of others, continuous learner
• Tenacious and resilient – is not easily overwhelmed by challenges, delivers on commitments, operates with urgency.

Bonus Qualifications

• Prior experience in a Quality Control laboratory or setting.
• Prior experience in a regulated environment
• Knowledge of cGMP working environment

*Salary will be commensurate with experience and qualifications; candidates with relevant prior co‑op experience and/or critical skills may receive a higher hourly rate.