Senior Scientist, Bioinformatics Engineer

Location: Warsaw, Poland
Hybrid model of work: 3 days in office, 2 remote per week

At AstraZeneca, we are combining cutting-edge science, data, and artificial intelligence to transform how we discover and develop medicines. As part of Data Sciences and Quantitative Biology (QuBi) this role will work in close collaboration with a group of chemical biology and proteomics scientists and QuBi Bioinformaticians supporting therapeutic areas across AstraZeneca, offering a unique opportunity to contribute to and apply new digital and AI capabilities.

Based at Warsaw, Poland, you will work at the intersection of mass spectrometry-based (MS) proteomics and computational biology, helping to build the data platform and analytical foundations that allow scientists to explore high-throughput proteomics data from mass-spectrometer and emerging molecular assays. This is a hands-on technical role for someone who combines practical bioinformatics, workflow development, and data engineering skills with strong proteomics expertise to deliver robust, scalable workflows, data infrastructure, and tools that scientific teams can rely on.

What  you will do

As Senior Scientist - Bioinformatics Engineer within QuBi, you will: 

Workflow development and automation

• Design, implement and maintain reproducible end-to-end pipelines for the processing, analysis, interpretation and visualisation of high-throughput proteomics data.

• Develop portable and versioned computational workflows using technologies such as Nextflow, Snakemake or comparable workflow frameworks.

• Containerise analytical environments using technologies such as Docker and deploy workflows across HPC and cloud computing environments.

• Build robust quality control, validation and provenance into computational workflows to produce reproducible, interpretation-ready outputs.

• Apply software engineering best practices including version control, code review, automated testing, CI/CD, documentation and release management.

• Design workflows and analytical components with appropriate interfaces, metadata and execution standards to enable programmatic reuse, including by emerging AI-enabled and agentic scientific workflows.

Data management and infrastructure

• Develop and maintain scalable data models and storage strategies for proteomics raw data, intermediate results, processed datasets and analytical outputs.

• Establish metadata and provenance approaches that connect experimental context, sample information, analytical parameters, workflows and results.

• Integrate chemical biology, experimental and proteomics metadata to create harmonised, analysis-ready datasets that enable reuse and biological insight across studies.

• Apply FAIR data principles and appropriate data governance, access control and retention practices in collaboration with relevant technology and security teams.

• Contribute to searchable analytical data products and result databases using technologies such as Snowflake, PostgreSQL or equivalent platforms.

• Develop scientific interfaces and applications using technologies such as R Shiny, Streamlit or comparable frameworks where appropriate.

• Help make proteomics data and outputs discoverable, reusable and suitable for downstream advanced analytics, machine learning and AI applications

Required qualifications

• Ph.D. (or Masters with 3 years of experience) in bioinformatics, computational biology, computer science, or a related discipline

• Demonstrated experience in bioinformatics and data analysis, with the ability to develop and apply reproducible analytical workflows for complex biological datasets.

• Experience with cloud platforms (such as AWS or Azure), covering core concepts like virtual machines, storage buckets, and basic cloud networking.

• Experience developing reproducible computational workflows using Nextflow or Snakemake, together with containerised Linux environments.

• Experienced in designing scalable omics data models and in applying FAIR data principles and data governance.

• Experience with programming and data analysis in languages such as R and/or Python, and familiarity with scientific software development best practices.

• Proficiency with version control (Git/GitHub) and collaborative software development practices.

• Ability to work as an independent contributor while collaborating effectively across multidisciplinary teams.

• Strong communication skills, with the ability to explain complex scientific and technical concepts to diverse audiences and support adoption of analytical solutions.

Preferred qualifications

• Experience in analyzing MS-based discovery proteomics data

• Experience developing or applying machine learning and AI for scientific data analysis, interpretation, or workflow automation.

• Experience in multi-omics analysis is a plus

• Solid grounding in the statistics of high-dimensional omics data

• A track record of scientific innovation demonstrated through publications, conference presentations, open-source contributions, software products, or deployed analytical tools in bioinformatics, AI, or data science.

How we do it

At AstraZeneca, we're dedicated to being a Great Place to Work, where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference in medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development.

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

About Us

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We

focus on discovering, developing and commercialising prescription medicines for some

of the world’s most serious diseases. But we are more than one of the world’s leading

pharmaceutical companies.

At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered

to push the boundaries of science, challenge convention and unleash your entrepreneurial

spirit. To embrace differences and take bold actions to drive the change needed to meet

global healthcare and sustainability challenges.

There is no better place to make a difference in medicine, patients, and society. An inclusive

culture where you will connect different thinking to generate new and valuable opportunities.

Where you will find a commitment to lifelong learning, growth and development for all.

Championing Inclusion and Diversity

Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients.

Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking.

Life at AstraZeneca

We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions.

As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential.

Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.