Sr. Director, Supply Chain

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com . Summary The Sr Director of Supply Chain for the Commercial Production Lab provides strategic and operational leadership across the end-to-end supply chain, including demand and supply planning, inventory management, procurement, warehouse operations, logistics, supplier management, and third-party kit fulfillment. The role ensures uninterrupted support of laboratory operations and patient testing while optimizing inventory investment, service levels, supplier performance, cost, and operational efficiency. The Sr Director leads cross-functional planning and partners with Commercial Production Lab Operations, Quality, Regulatory, Finance, Accounting, and external providers to align supply chain capabilities with business growth, compliance requirements, and organizational objectives. The role also builds supply chain talent and uses data, systems, and analytics to improve visibility, resilience, scalability, and decision-making. Job Responsibilities Develop and execute the end-to-end supply chain strategy for Commercial Production Lab operations, ensuring material availability, service, quality, compliance, cost-effectiveness, and scalability in support of uninterrupted laboratory operations and patient testing. Lead the Sales, Inventory, and Operations Planning (SIOP) process, integrating demand forecasts, supply plans, inventory strategies, capacity considerations, and business objectives to support organizational growth and operational performance. Provide strategic oversight of demand planning, inventory management, materials control, warehousing, distribution, and third-party kit fulfillment operations, balancing service levels, production readiness, and working capital objectives. Establish and lead supplier, logistics, and external partner strategies, including supplier qualification, performance management, contract oversight, continuity planning, and executive-level relationship management. Ensure continuity of supply through proactive risk management, business continuity planning, alternate sourcing strategies, and resolution of supply, inventory, and logistics constraints that may impact laboratory operations or patient testing. Partner with Commercial Production Lab Operations, Quality, Regulatory, Accounting, and external providers to align supply chain capabilities with operational requirements, quality standards, and business objectives. Oversee supply chain systems, planning processes, master data, inventory controls, and reporting capabilities while leveraging ERP/MRP systems, analytics, and performance dashboards to improve visibility, decision-making, and operational efficiency. Define and own supply chain performance metrics, operating reviews, and executive reporting, including forecast accuracy, inventory performance, supplier performance, service levels, cost management, and operational risk indicators. Build, lead, and develop a high-performing supply chain organization by establishing clear accountabilities, developing talent, supporting succession planning, and fostering a culture of accountability, continuous improvement, and operational excellence. Develop and manage supply chain operating plans and budgets while driving initiatives that improve efficiency, resilience, scalability, and overall business performance. Perform other duties as assigned in support of the team or department. People Manager Yes Serves as a “leader of leaders,” guiding managers and teams composed of highly trained, credentialed professionals in strategic sourcing, demand and supply planning, inventory management, supplier relationship management, and warehousing and distribution. This position may also directly supervise non-supervisory team members. Provides mentorship and strategic direction to functional leads and professionals involved in high-impact processes. Cultivates a culture of accountability and continuous learning across credentialed, high-performing teams. Education, Experience, and Skills Bachelor’s degree in Supply Chain, Operations, Business, Engineering, Logistics, Finance or related field. 12+ years of progressive experience in supply chain, operations, or related disciplines, including significant experience leading complex, cross-functional organizations and developing leaders. Demonstrated expertise across demand and supply planning, inventory optimization, supplier management, warehousing, logistics, risk management, and business continuity, with the ability to translate functional expertise into enterprise-wide supply chain strategy. Proven experience leadingSIOP/S&OP or an equivalent integrated planning process, including the ability to align cross-functional stakeholders, establish priorities, evaluate risks and tradeoffs, and influence senior leadership decision-making. Strong understanding of ERP/MRP systems, supply chain master data, forecasting and inventory analytics, dashboards, and performance management. Consistently demonstrates strong business judgement, accountability, and a results-oriented approach, with a track record of delivering sustainable improvements in organizational and business performance. Strong leadership, communication, and cross-functional collaboration skills. Work Environment This is a hybrid position requiring both in-office and remote work. The employee will work from our office location in Gaithersburg, MD and remotely from a home office or other suitable location with reliable high-speed internet access. In-office work is performed in a professional office setting with standard lighting, temperature control, and low to moderate noise levels. Remote work is performed in a climate-controlled environment. Standard office equipment including computer, phone, and video conferencing tools are used in both settings. Your standard work schedule and hours will be established in collaboration with your leader and may be adjusted to align with evolving business needs. Physical Demands This is a sedentary role with physical demands including: Sitting for extended periods (up to 8 hours per day) Repetitive use of hands and fingers for typing and mouse operation Visual acuity for reading computer screens and documents Ability to communicate effectively in person, by phone, and via video Occasional standing, walking, and reaching for files or supplies Occasional lifting of up to 15 pounds (files, office supplies, equipment) Ability to commute to office location as required Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position. Pay Transparency, Budgeted Range $220,000 — $240,000 USD A culture that plays to win, because patients are counting on us​ At GeneDx, we're driven by urgency and purpose: helping patients get diagnosed earlier. Our mission, to empower everyone to live their healthiest life through genomics, drives our team to make a tangible impact each day – and shapes our culture where high standards, strong teamwork, and meaningful ownership are the norm. We act with intention, support one another, and deliver work we're proud to put our names on.​ Here’s what you can expect day to day:​ 1. Play like a champion (step up, redefine what’s possible, own it)​ We bring energy, focus, and a bias for action. We step up, take initiative, and deliver on our commitments – with quality, speed, and care.​ 2. Think bigger (stretch beyond, courage not consensus)​ We push past the obvious. We challenge assumptions, raise the bar, and make thoughtful, decisive calls — choosing progress over perfection.​ 3. Grow fast (be curious, speak up, be agile)​ We stay curious, ask questions, and share direct feedback with respect. We adapt quickly and keep learning through collaboration and continuous improvement.​ If you’re motivated by meaningful work, a fast-moving environment, and teammates who care deeply about outcomes, you’ll thrive at GeneDx. At GeneDx, we believe in taking care of our people. We provide competitive compensation and benefits that reflect local market practices and legal requirements in each country where we operate, helping employees thrive both professionally and personally. We welcome everyone regardless of their background. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, protected veteran status, disability, age, and other characteristics protected by law. GeneDx is a place where people from all backgrounds can make an impact. All privacy policy information can be found here .