US Medical Head, One Rare

Job title: US Head Medical Lead, One Rare

• Location: Cambridge, MA or Morristown, NJ

About the Job

The US Medical Head, One Rare serves as a member of the Sanofi Specialty Care North America Medical Leadership Team and leads the creation and execution of world-class medical strategy for our combined Rare Disease and Rare Blood Disorders (RBD) portfolio, including hemophilia, rare hematology, and our broader rare disease pipeline. This role collaborates closely with Global Medical teams, Research & Development, Drug Safety, Sales & Marketing, Regulatory, and other stakeholders to deliver on medical strategy across the One Rare organization, and provides direct leadership to both home-office and field-based medical teams, including the One Rare Field Lead and their team.

Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.

About Sanofi

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system — and innovative pipeline — enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main Responsibilities

• Provide inspirational leadership and focus to the One Rare US Medical team, fostering a culture of teamwork, engagement, and performance, while attracting, developing, and retaining top talent across both Rare Disease and RBD.

• Lead the development, execution, and monitoring of medical brand strategy across the One Rare portfolio, working with functional leads on tactics and associated budgets.

• Own and be accountable for the One Rare US medical budget.

• Lead the US OneRare stakeholder engagement strategy, developing and maintaining key opinion leader relationships across the franchise and the broader healthcare community, and representing One Rare US Medical and Sanofi Specialty Care to key external audiences, including HCPs, thought leaders, medical associations, and other organizations.

• Partner with our Patient Advocacy team to ensure the patient voice informs One Rare medical strategy and stakeholder engagement.

• Help steer One Rare's medical strategy and ways of working in line with North America Medical's broader transformation toward data-driven, AI-enabled evidence generation and HCP and patient engagement.

• Partner with Integrated Evidence & Patient Outcomes — including Medical Value & Organized Systems Engagement and our Payer Account Director teams — to strengthen evidence generation, real-world data, and patient outcomes measurement across the One Rare portfolio.

• Lead local data generation plans that supplement the core registration data generated by the clinical development plan, in support of local market access and product life cycle management.

• Support patient-finding and diagnostic initiatives — including EHR-based diagnostic algorithms and digital biomarker tools — to help shorten the diagnostic journey for rare disease patients and connect them to care sooner.

• Ensure appropriate review and approval of medical and scientific content across Regulatory, Safety, Scientific, Medical, and Commercial outputs.

• Oversee implementation of training and education events for internal and external stakeholders.

• Support the US implementation of registries and humanitarian programs for rare disease.

• Ensure team compliance with FDA, OIG, HIPAA, and other ethical and regulatory guidelines relevant to the pharmaceutical industry, along with internal standard operating procedures.

• Collaborate with other therapeutic areas to leverage One Rare Medical expertise and programs as appropriate.

• Travel as required to support and attend conferences, symposia, and other important meetings (up to 50%).

About You

Basic Qualifications

• Advanced degree in a scientific discipline (e.g., MD, PhD, PharmD).

• Minimum of 15 years of experience in Medical or related areas, including at least 7 years leading a medical function.

• Minimum of 10 years of experience leading high-performing teams, with a proven track record of developing talent.

• Experience in Rare Disease and/or Rare Blood Disorders is required.

• Strong track record in developing and executing medical strategies in key markets.

• Proven track record of building and maintaining a KOL network across a region.

• Experience working across and building effective partnerships between departments in a global, matrixed organization.

• Extensive experience and an excellent track record in dealing with safety issues.

• Must possess the highest ethical standards and the knowledge and ability to comply with all relevant ethical, regulatory, and legal standards.

Preferred Qualifications

• Advanced training or certification in Hematology, and/or experience in Rare Disease Medical.

• Entrepreneurial and strategic vision, with excellence in strategy development and delivery.

• Excellent people and budget management abilities, including the ability to lead and organize others without direct authority.

• Outstanding interpersonal, communication, negotiation, and networking skills.

• Critical thinking and problem-solving mindset, balanced with creative thinking.

• Excellent at planning, project, time, budget, and resource/portfolio management.

• Able to multi-task and perform well under pressure.

• Strong understanding of organizational and inter-cultural sensitivities, with the ability to apply this to day-to-day practice.

• Fluent in English with superb written and verbal communication skills; fluency in additional languages is a plus.

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness program

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

Sanofi US endeavours to make our career center accessible to any and all users. If you are experiencing difficulty and need assistance applying online, please call 1-866-SANOFI2 (1-866-726-6342) or click here

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

About Us

We are an R&D driven, AI-powered biopharma company committed to improving people’s lives and creating compelling growth. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives.

We want to build a healthier, more resilient world, and turn the impossible into the possible by discovering, developing, and delivering medicines and vaccines for millions of people around the world.

Discover more about us visiting www.sanofi.com or via our movie We are Sanofi

Why Sanofi

Start a career that makes a difference.

Reinvention is in our DNA. It’s what drove our evolution from a small French enterprise to one of the world’s leading biopharma companies. Whether it’s using AI to shorten drug-discovery times or building trust in healthcare, you could be helping our teams make life better for patients, partners, and communities.

This is where you grow your career. We open the door for you to explore new opportunities, push your limits, and connect with people who are driven by a shared purpose: we chase the miracles of science to improve people’s lives.