Senior Metabolomics Assay Specialist

Job Title: Senior Metabolomics Assay Specialist

Location: United Arab Emirates (Remote)

Employment Type: Full-Time

Work Arrangement: 100% Remote — Work From Home

Level: Senior

About the Role

We are seeking an experienced Senior Metabolomics Assay Specialist to provide technical leadership in the development, optimization, validation, and analytical interpretation of metabolomics assays. The role focuses on designing robust analytical workflows for the detection, identification, and quantification of metabolites in biological, pharmaceutical, and research samples. The successful candidate will provide remote technical oversight, review analytical performance, assess complex datasets, and collaborate with laboratory scientists, bioinformaticians, research teams, and quality professionals to support reliable and reproducible metabolomics results.

Key Responsibilities

• Lead the development and optimization of targeted and untargeted metabolomics assay strategies.
• Design analytical workflows for metabolite extraction, sample preparation, separation, detection, and quantification.
• Provide technical guidance on liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS), and related analytical platforms.
• Evaluate assay suitability for different sample matrices, including plasma, serum, urine, tissue, cell extracts, and other biological materials.
• Review analytical methods for metabolite coverage, sensitivity, selectivity, reproducibility, and quantitative performance.
• Oversee the technical assessment of sample preparation procedures, extraction efficiency, derivatization, and metabolite stability.
• Evaluate internal standards, calibration strategies, quality control samples, and analytical reference materials.
• Review method validation and verification activities, including accuracy, precision, linearity, recovery, matrix effects, and limits of detection and quantification.
• Assess analytical batch performance, system suitability, retention time consistency, signal quality, and instrument drift.
• Review metabolite identification, annotation, and quantification workflows.
• Provide guidance on data normalization, missing-value assessment, batch correction, and quality control procedures.
• Interpret complex metabolomics datasets and identify meaningful metabolic patterns and analytical trends.
• Collaborate with bioinformatics and data science teams on statistical analysis, pathway enrichment, and metabolite profiling.
• Investigate analytical discrepancies, unexpected results, contamination signals, and potential sources of measurement bias.
• Review analytical protocols, SOPs, validation reports, technical summaries, and controlled laboratory documentation.
• Support the development of metabolomics assay transfer and lifecycle management strategies.
• Assess the impact of changes in sample handling, storage conditions, analytical platforms, and laboratory procedures on assay performance.
• Contribute to research projects involving metabolic biomarkers, disease-associated metabolic changes, pharmaceutical development, and biochemical pathways.
• Monitor advances in metabolomics technologies, analytical chemistry, mass spectrometry, and relevant scientific standards.
• Recommend improvements to analytical workflows, data integrity controls, reproducibility, and reporting practices.

Qualifications and Experience

• Bachelor's or master's degree in Analytical Chemistry, Biochemistry, Metabolomics, Molecular Biology, Biotechnology, Pharmaceutical Sciences, or a related discipline.
• A doctoral degree or equivalent research experience is advantageous for advanced research-focused responsibilities.
• Significant experience in metabolomics assay development, analytical chemistry, mass spectrometry, or biochemical analysis.
• Strong practical knowledge of LC-MS and/or GC-MS analytical workflows.
• Experience with targeted and untargeted metabolomics methodologies.
• Understanding of metabolite extraction, sample preparation, derivatization, and analytical separation techniques.
• Knowledge of biological sample matrices and factors affecting metabolite stability and measurement.
• Experience evaluating assay performance, including precision, accuracy, recovery, linearity, sensitivity, and matrix effects.
• Familiarity with internal standards, calibration curves, pooled quality control samples, and reference materials.
• Understanding of metabolite identification, annotation, quantification, and pathway analysis.
• Experience reviewing complex analytical datasets and identifying sources of technical variability.
• Familiarity with metabolomics data processing software and bioinformatics tools.
• Knowledge of statistical methods, data normalization, batch correction, and quality control assessment.
• Understanding of laboratory quality systems, good documentation practices, and applicable data integrity principles.
• Experience preparing technical reports, analytical protocols, validation documents, and scientific summaries.
• Strong analytical thinking, scientific communication, and problem-solving skills.
• Ability to coordinate effectively with multidisciplinary research and laboratory teams in a fully remote environment.

What We Offer

• Fully remote working arrangement within the UAE employment framework, subject to applicable eligibility and authorization requirements.
• Opportunity to contribute to advanced metabolomics research and analytical development programs.
• Collaboration with multidisciplinary specialists in analytical chemistry, biotechnology, bioinformatics, and pharmaceutical sciences.
• Professional development in mass spectrometry, metabolomics technologies, and advanced analytical methods.
• A senior technical role with opportunities to improve assay performance, scientific reproducibility, and data quality.

How to Apply

Interested candidates should submit an updated CV highlighting their metabolomics experience, mass spectrometry expertise, assay development background, analytical validation capabilities, and relevant scientific qualifications.

Application Subject: Application – Senior Metabolomics Assay Specialist (UAE Remote)

• Important Note: This is a fully remote technical oversight, analytical review, and scientific coordination role. Physical sample collection, sample preparation, laboratory testing, instrument operation, and experimental procedures must be performed by appropriately qualified personnel at authorized facilities. The specialist may provide remote technical guidance, review analytical data, assess assay performance, and support scientific investigations. Clinical diagnostic interpretations, regulated laboratory approvals, and formal regulatory submissions must be completed by appropriately licensed or authorized personnel where required. Candidates should confirm applicable employment arrangements, residency requirements, and work authorization before accepting an offer.